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San Diego, named after Saint Didacus, is the eighth-largest city in the United States and second-largest city in California, after Los Angeles, with a population of 1,359,132 on a land area of 372.1 square miles. The urban area of San Diego extends beyond the administrative city limits with a population of 2,880,000. Also, this is part of a megalopolis called the San Diego and Los Angeles metropolitan areas with a population of approximately 22 million. San Diego is located on the Pacific Ocean at the southernmost end of the west coast of the continental United States.
The city is also the county seat of San Diego County as well as the economic center of the San Diego–Carlsbad–San Marcos Metropolitan Area considered congruent with the county. San Diego was rated the fifth-best place to live in the United States by Money magazine. San Diego is the fifth-wealthiest city in the United States and the 9th safest city in the top 10 list of safest cities in the U.S. San Diego's top four industries are manufacturing, defense, tourism, and agriculture. San Diego's economy is largely composed of agriculture, biotechnology/biosciences, computer sciences, electronics manufacturing, defense-related manufacturing, financial and business services, ship repair, ship construction, software development, telecommunications, wireless research, and tourism. The presence of the University of California, San Diego, with the affiliated UCSD Medical Center promotes research in biotechnology.
The area of San Diego has been inhabited for more than 10,000 years by the Kumeyaay Indians. The first European to visit the region was Portuguese-born explorer Juan Rodríguez Cabrillo sailing under the flag of Castile, who sailed his flagship San Salvador from Navidad, New Spain. In 1542, Cabrillo claimed the bay for the Spanish Empire and named the site San Miguel. In November of 1602, Sebastián Vizcaíno was sent to map the California coast. Arriving on his flagship San Diego, Vizcaíno surveyed the harbor and what are now Mission Bay and Point Loma and named the area for the Catholic Saint Didacus, a Spaniard more commonly known as San Diego de Alcalá. On November 12, 1602, the first Christian religious service of record in Alta California was conducted by Friar Antonio de la Ascensión, a member of Vizcaíno's expedition, to celebrate the feast day of San Diego.